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The behaviour of these functions is affected by settings in php.ini.

Here's a short explanation of the configuration directives.

mysqlnd_memcache.enable integer

Enables or disables the plugin. If disabled, the extension will not plug into mysqlnd to proxy internal mysqlnd C API calls.

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This option is mainly used by developers to build this extension statically into PHP. General users are encouraged to build this extension as a shared object, and to unload it completely when it is not needed.